Diagnosis of Microvascular Invasion in Hepatocellular Carcinoma Using Intravoxel Incoherent Motion Diffusion Weighted Imaging
10.3870/j.issn.1672-0741.24.07.011
- VernacularTitle:体素内不相干运动扩散加权成像对肝细胞癌微血管侵犯的诊断价值
- Author:
Wenzhong YI
1
;
Can CHEN
;
Zhiqun MAO
Author Information
1. 湖南医药学院总医院影像中心,怀化 418000
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
microvascular invasion;
intravoxel incoherent motion;
magnetic resonance imaging
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2025;54(1):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of intravoxel incoherent motion diffusion weighted imaging(IVIM)in preopera-tive diagnosis of microvascular invasion(MVI)in hepatocellular carcinoma(HCC).Methods A retrospective analysis was con-ducted on the imaging data of 38 hepatocellular carcinoma patients who underwent surgical resection at Hunan Medical College General Hospital from 2019 to 2022.According to postoperative pathology results,they were divided into MVI positive group and MVI negative group.The apparent diffusion coefficient(ADC)of DWI parameters,the true diffusion coefficient(D),perfu-sion related diffusion coefficient(D),and perfusion score(f)of IVIM parameters were measured before surgery in HCC pa-tients.The risk factors affecting the occurrence of MVI in HCC were analyzed,and the diagnostic efficacy of subject operating characteristic curve(ROC)was evaluated for MVI.Results The ADC and D values of the MVI positive group were lower than those of the negative group,with statistical differences(both P＜0.05).The area under the D-value curve(AUC),specificity,and sensitivity were 0.741,68％,and 94％,respectively.The area,specificity,and sensitivity under the ADC value curve were 0.714,50％,and 88％,respectively,The area under the curve for the combined diagnosis of MVI by two indicators was 0.832,with a sensitivity of 94％and a specificity of 77％.Conclusion The IVIM parameter D value and DWI parameter ADC value can help to predict microvascular infiltra-tion in hepatocellular carcinoma before surgery,and the diagnostic efficacy of D value is superior to ADC value.IVIM imaging can im-prove the accuracy of preoperative prediction of microvascular invasion in hepatocellular carcinoma.
