Correlation between acute carbon monoxide poisoning-induced myocardial damage and delayed encephalopathy
10.3760/cma.j.cn311847-20210205-00050
- VernacularTitle:急性一氧化碳中毒心肌损害与迟发脑病的相关性研究
- Author:
Fei YAO
1
;
Xin XIAO
1
;
Jinshan WO
1
Author Information
1. 266000 山东省青岛，青岛大学（现工作单位为海军第九七一医院军事医学与特种医学科）
- Publication Type:Journal Article
- Keywords:
Carbon monoxide poisoning;
Myocardial damage;
Electrocardiogram;
Delayed encephalopathy
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(5):599-601,606
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between myocardial damage and delayed encephalopathy in patients with acute carbon monoxide poisoning (ACOP).Methods:The clinical data of 205 patients with ACOP treated in No. 971 Hospital of the PLA Navy from November 2016 to November 2020 were retrospectively analyzed. The patients were divided into encephalopathy group ( n=110) and non-encephalopathy group ( n=95) based on whether they had delayed encephalopathy. Myocardial damage-related indicators and the results of electrocardiogram (ECG) analysis within 24 hours after admission were compared between the two groups. Results:The levels of serum creatine kinase (CK), creatine kinase isoenzyme (CK-MB), cardiac troponin I (cTnI), myoglobin (Mb), and lactate dehydrogenase (LDH) in the encephalopathy group were higher than those in the non-encephalopathy group, with statistically significant differences ( P<0.01). The incidences of ECG ST-T changes and atrioventricular block in the encephalopathy group were higher than those in the non-encephalopathy group, with statistically significant differences ( P<0.05). Conclusion:Myocardial damage-related indicators and the early ECG results in patients with ACOP are closely correlated with the incidence of delayed encephalopathy.
