Evaluation the clinical efficacy of vitrectomy for diabetic retinopathy by optical coherence tomography angiography(OCTA)
10.16352/j.issn.1001-6325.2025.08.1078
- VernacularTitle:应用OCTA评估糖尿病性视网膜病变玻璃体切割术后的临床效果
- Author:
WULAN
1
;
Chang WEI
1
;
Yingzhen LI
1
;
Chunsheng LUAN
1
Author Information
1. 大庆油田总医院眼科,黑龙江大庆 163000
- Publication Type:Journal Article
- Keywords:
diabetic retinopathy;
vitrectomy;
optical coherence tomography angiography(OCTA);
vessel density of superficial cap-illary plexus;
central macular thickness
- From:
Basic & Clinical Medicine
2025;45(8):1078-1082
- CountryChina
- Language:Chinese
-
Abstract:
Objective OCTA analysis was employed to assess the alterations in retinal microcirculation following vitrectomy in patients with diabetic retinopathy.Methods The clinical data of 60 eyes from 60 diabetic retinopathy patients who accepted vitrectomy from Mar.2022 to May.2024 in Daqing Oilfield General Hospital were analyzed prospectively.The preoperative and postoperative outcomes of best corrected visual acuity(BCVA),intraocular pres-sure(IOP),and optical coherence tomography angiography(OCTA)were compared at baseline,as well as at 1 day,1 week,1 month,and 3 months following surgery.Results There was statistically significant differences in IOP between preoperative and postoperative 1 day and 1 week(P＜0.01).There were significant differences in BCVA and CMT observed prior to surgery,as well as at 1 day,1 week,1 month,and 3 months post-surgery(P＜0.01).FAZ and RPC exhibited significant differences prior to surgery,as well as at 1 week,1 month,and 3 months postoperatively(P＜0.01).The SVD,DVD,and RNFL exhibited significant differences prior to surgery and at 1 month and 3 months postoperatively(P＜0.01).Conclusions Vitrectomy can substantially enhance the visual acuity of patients with DR,and this improvement tends to stabilize approximately one month post-surgery,potential-ly correlating with the stability of central macular thickness(CMT)observed in patients at that time.The procedure can significantly decrease intraocular pressure in patients,and FAZ along with the radial peripapillary capillaries(RPC)in the macular region exhibited earlier improvement postoperatively.
