Effect of early hyperbaric oxygen therapy on prognosis of basal ganglia hemorrhage patients without hematoma evacuation
10.3760/cma.j.cn311847-2020200702-00273
- VernacularTitle:早期高压氧治疗对未行血肿清除手术的基底节区脑出血患者预后的影响
- Author:
Yifang WANG
1
;
Anni JI
;
Jirong GAO
;
Aiping WANG
;
Xilin SUN
;
Xia WANG
;
Zhengwei WANG
;
Shide QIAN
Author Information
1. 210002 南京，南京紫金医院
- Publication Type:Journal Article
- Keywords:
Basal ganglia;
Cerebral hemorrhage;
Edema;
HBO
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(4):442-444,483
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of early hyperbaric oxygen therapy (HBOT) on neurological function recovery of basal ganglia hemorrhage patients who didn’t receive hematoma evacuation.Methods:A total of 41 basal ganglia hemorrhage patients treated in Nanjing Zijin Hospital and PLA Air Force Hospital of The Eastern Theater Command from January 2015 to January 2020 were included in this study. They did not undergo hematoma evacuation surgery due to small hematoma volume, 18 of whom received early HBOT (treatment group), and the remaining 23 patients received the same HBOT two weeks after hemorrhage (control group). The hematoma volume and the changes of perihematomal edema (PHE) were observed using regular head CT scan, and the incidences of PHE expansion in the two groups were compared on the 10th day after the hemorrhage. All the 41 patients’ neurological functions were assessed by the National Institutes of Health stroke scale (NIHSS) and Glasgow outcome scale (GOS) upon their admission and three months after admission.Results:No re-hemorrhage was found in any patient on the head CT scan. On the 10th day after admission, the incidence of PHE expansion was 16.7% in the treatment group and 91.3% in the control group, respectively, the difference was statistically significant ( P<0.01). After three months of treatment, the NIHSS scores of both groups were decreased, and the GOS scores of both groups were increased. The NIHSS score of the treatment group was lower than that of the control group, while the GOS score in the treatment group was higher than that of the control group, both with statistically significant differences ( P<0.05). Conclusion:Early HBOT is a safe treatment for basal ganglia hemorrhage patients without hematoma evacuation, and it can reduce the occurrence of PHE and improve the prognosis of patients.
