Application of remimazolam combined with nalbuphine anesthesia in painless gastroscopy
- VernacularTitle:瑞马唑仑联合纳布啡麻醉在无痛胃镜检查中的应用
- Author:
Zhi-jie LIU
1
;
Yong-xue CHEN
;
Xing ZHAO
;
Yang GAO
;
Si-yuan LI
Author Information
- Publication Type:Journal Article
- Keywords: painless gastroscopy; nalbuphine; remimazolam; respiratory rate; recovery quality
- From: Journal of Regional Anatomy and Operative Surgery 2025;34(8):698-701
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the anesthetic effects of remimazolam combined with nalbuphine on patients undergoing painless gastroscopy.Methods A total of 120 patients who underwent painless gastroscopy in Handan Central Hospital from August 2019 to May 2021 were selected and randomly divided into the observation group(60 cases)and the control group(60 cases).Patients in the observation group anesthetized with remimazolam and nalbuphine,while patients in the control group anesthetized with propofol and alfentanil.The vital signs,sedative effect,recovery quality,cognitive function,and adverse reactions of patients were compared between the two groups.Results The heart rate(HR),respiratory rate(RR),and the level of pulse oxygen saturation(SpO2)of patients in the observation group were significantly higher than those in the control group(P<0.05).Five minutes after the examination,the Narcotrend score of patients in the observation group was significantly lower than that in the control group(P<0.05).The time from the last administration to awakening,the time from gastroscopy removal to awakening,and the time of leaving the anesthesia recovery room of patients in the observation group were significantly shorter than those in the control group(P<0.05).Five minutes after the examination,the score of the mini-mental state examination(MMSE)of patients in the observation group was significantly higher than that in the control group(P<0.05),while the incidence of adverse reactions was significantly lower than that in the control group(P<0.05).Conclusion The application of remimazolam combined with nalbuphine anesthesia in painless gastroscopy has a relatively ideal effect,which can effectively reduce the adverse reactions of patients and promote rapid postoperative recovery.
