Multimodal MRI features of cerebral small vessel disease combined with type 2 diabetes mellitus
- VernacularTitle:2型糖尿病脑小血管病的多模态MRI特征分析
- Author:
Jing WANG
1
;
Hang PAN
;
Yan-ling ZHENG
;
Zi-wen LIANG
;
Yu-lin WANG
;
Qiu-guo OU
;
Fan-ying GUAN
;
Hai-yan TAO
;
Lei SONG
;
Rui TANG
Author Information
- Publication Type:Journal Article
- Keywords: MRI; type 2 diabetes mellitus; diabetic angiopathy; cerebral small vessel disease; imaging features
- From: Journal of Regional Anatomy and Operative Surgery 2025;34(8):689-692
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the imaging features of cerebral small vessel disease in patients with type 2 diabetes mellitus by multimodal MRI.Methods The clinical data of 160 patients with cerebral small vessel disease admitted to our hospital from January to December 2020 were retrospectively analyzed.According to whether they were complicated with type 2 diabetes mellitus,they were divided into the diabetic group and the non-diabetic group,with 80 cases in each group.Both groups underwent multimodal MRI scans.And the severity of lacunar infarction,the severity of subcortical and periventricular white matter lesions,white matter integral and cerebral microbleeds of patients in the two groups were compared.Results The severity of lacunar infarction(χ2=34.076,P=0.001),subcortical white matter lesions(χ2=25.000,P=0.001),periventricular white matter lesions(χ2=22.895,P=0.001)and white matter integral(t=12.370,P=0.001)of patients in the diabetic group were significantly higher than those in the non-diabetic group.No cerebral microbleeds were detected in either group of patients.Conclusion Patients with cerebral small vessel disease and type 2 diabetes mellitus show characteristic multimodal MRI changes.The increase in the number of lacunar infarction lesions and the aggravation of white matter lesions can be used as the characteristic imaging basis for the diagnosis of type 2 diabetes mellitus related cerebral small vessel disease.
