Effects of different courses of hyperbaric oxygen therapy on the clinical efficacy, neurological function, and negative emotions of patients with spinal cord injury
10.3760/cma.j.cn311847-20201126-00445
- VernacularTitle:不同疗程高压氧治疗对脊髓损伤患者疗效、神经功能及消极情绪的影响
- Author:
Liangliang GAO
1
;
Quan HUANG
;
Tulin HUANG
;
Tao YANG
;
Hongbin SHAN
;
Zhenghai SHAO
Author Information
1. 200003 上海，海军军医大学长征医院骨科
- Publication Type:Journal Article
- Keywords:
Spinal cord injury;
Hyperbaric oxygen therapy;
Neurological function;
Negative emotion
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(3):319-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of different courses of hyperbaric oxygen (HBO) therapy on the clinical efficacy, neurological function, and negative emotions of patients with spinal cord injury.Methods:The clinical data of 126 patients with spinal cord injury treated in the Department of Orthopedics of Changzheng Hospital Affiliated to Naval Medical University and the Department of Orthopedics of Shanghai Kaiyuan Orthopedic Hospital from January 2017 to October 2019 were retrospectively analyzed. According to whether or not the patients received HBO therapy after surgery and different courses of HBO therapy, the patients who did not receive HBO therapy were taken into the control group ( n=32), the patients who received 1-2 courses of HBO therapy were taken into the observation group A ( n=32), the patients who received 3-4 courses of treatment were taken into the observation group B ( n=31), and the patients who received 5-6 courses of treatment were taken into the observation group C ( n=31). All patients were evaluated by the American Spinal Injury Association (ASIA) Impairment Scale, functional independence measure (FIM), zung self-rating anxiety scale (SAS), and zung self-rating depression scale (SDS) before and after treatment to assess the clinical efficacy. Results:After treatment, the scores of ASIA pin prick and light touch sensation in four groups were significantly improved compared with those before treatment ( P<0.05), the improvements of observation group A, B, and C were better than those of the control group, and the improvements of observation group B and C were better than those of the observation group A ( P<0.05). After treatment, ASIA motor scores and FIM scores of the four groups were significantly improved compared with those before treatment, and the differences were statistically significant ( P<0.05). After treatment, ASIA motor scores and FIM scores of observation group A, B, and C were higher than those of the control group, and the improvements of observation group B and C were better than those of the observation group A, with statistically significant differences ( P<0.05). After treatment, SAS scores and SDS scores of the four groups were significantly decreased compared with those before treatment, and the differences were statistically significant ( P < 0.05). The scores of SAS and SDS in the observation group A, B, and C after treatment were lower than those of the control group, and the differences were statistically significant ( P<0.05). Conclusion:Hyperbaric oxygen can effectively alleviate the spinal cord injury symptoms of patients, improve their neurological function, and reduce their negative emotions, and can exert better therapeutic effect after 3-4 treatment courses or more.
