A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion

VernacularTitle:以发热伴中性粒细胞升高性胸腔积液为主要表现的成人斯蒂尔病一例
Author: Chao NIU ¹ ; YuLin MAI ; HanXue LI ; JunYan QIAN ; Wei CAO
Author Information

1. 中国医学科学院北京协和医院感染内科,北京 100730;遵化市人民医院感染科,河北遵化 064200
Publication Type:Journal Article
Keywords: pleural effusion; exudative; adult-onset Still's disease; inflammation
From: Medical Journal of Peking Union Medical College Hospital 2025;16(4):1057-1061
CountryChina
Language:Chinese
Abstract: We report a case of adult-onset Still's disease(AOSD)presenting with fever,myalgia,and pleural effusion.The patient exhibited significantly elevated inflammatory markers and exudative pleural effusion with markedly elevated leukocyte count showing neutrophilic predominance.After comprehensive exclusion of infectious etiologies,the diagnosis of AOSD was established.Clinical symptoms resolved following anti-inflam-matory therapy with glucocorticoids and tocilizumab.This case highlights a critical clinical insight:while infec-tion is a common cause of elevated inflammatory markers,it is not an invariable etiology.In such presentations,meticulous clinical observation,thorough diagnostic screening,and systematic inference are es-sential for accurate diagnosis.