Clinical application of combined pancreaticobiliary brushing under endoscopic retrograde cholangiopancreatography in ampulla malignant tumours
- VernacularTitle:内镜逆行胰胆管造影术下胰胆管联合刷检在壶腹部恶性肿瘤中的临床应用
- Author:
Haowei CHEN
1
;
Changbao PAN
1
;
Weiwei CHEN
1
;
Juan CHEN
1
;
Denghao DENG
1
;
Qingcheng XU
1
Author Information
- Publication Type:Journal Article
- Keywords: hepatopancreatic ampulla malignant obstruction; endoscopic retrograde cholangiopancreatography(ERCP); combined pancreaticobiliary brushing; biliary duct brushing; cytobrush
- From: China Journal of Endoscopy 2025;31(4):39-43
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the clinical application value of combined pancreaticobiliary brushing under endoscopic retrograde cholangiopancreatography(ERCP)in the treatment of hepatopancreatic ampulla malignant tumours.Methods We retrospectively analyzed 59 patients from January 2013 to December 2023 for ERCP treatment of hepatopancreatic ampulla tumours,and performed combined pancreaticobiliary brushing(combined pancreaticobiliary brushing group,n=10)and biliary duct brushing alone(biliary duct brushing group,n=49)respectively,then compared the positive pathological detection rate of hepatopancreatic ampulla malignant tumours,the magnitude of bilirubin reduction,and the occurrence of postoperative complications between the two groups.Results The positive detection rate of combined pancreaticobiliary brushing for diagnosing ampulla malignant tumours was 70.0％(7/10),and the positive detection rate of biliary duct brushing alone was 22.4％(11/49),and the positive detection rate of pathology in the two groups was statistically significant(P＜0.05);No significant statistical difference was observed in the decrease of bilirubin between the two groups(P＞0.05);There were three cases of post-operative complications in the biliary duct brushing group.There were no postoperative complications in the combined pancreaticobiliary brushing group.Conclusion Compared with bile duct brushing alone,combined pancreaticobiliary brushing is more helpful for the diagnosis of malignant tumours,and does not increase the incidence of complications.It is worthy for clinical application.
