Efficacy of transurethral electrocoagulation combined with hyperbaric oxygen on hemorrhagic radiation cystitis
10.3760/cma.j.cn311847-20200430-00176
- VernacularTitle:经尿道膀胱电凝术联合高压氧治疗出血性放射性膀胱炎的疗效分析
- Author:
Baoyu LEI
1
;
Bo ZHAO
1
;
Yongjun YUE
1
;
Xiaohua WANG
1
;
Gang LI
1
;
Pengfei SHANG
1
Author Information
1. 046000 山西省长治，山西省长治医学院附属和济医院泌尿外科
- Publication Type:Journal Article
- Keywords:
Transurethral electrocoagulation;
Hyperbaric oxygen;
Hemorrhagic radiation cystitis;
Curative effect analysis
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(1):79-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of transurethral electrocoagulation combined with hyperbaric oxygen in the treatment of hemorrhagic radiation cystitis.Methods:A total of 76 patients with hemorrhagic radiation cystitis admitted to Heji Hospital Affiliated to Changzhi Medical College of Shanxi Province from June 2014 to April 2020 were selected as research subjects and randomly divided into control group ( n=38) and combination group ( n=38). The patients in the control group were treated with transurethral electrocoagulation, and the patients in the combination group were treated with hyperbaric oxygen on the basis of the treatments in the control group. The clinical efficacies of the two groups were compared. The urodynamic indexes were evaluated by urethral syndrome score (USS), overactive bladder symptom score (OABSS), interstitial cystitis symptom score (ICSI), and visual analogue scale (VAS) for pain. Results:After treatment, the total clinical effective rate of the combination group (94.74%, 36/38) was significantly higher than that of the control group (81.58%, 31/38), with statistically significant difference ( P<0.05). Compared with those before treatment, in both groups, the bladder capacity and micturition volume increased significantly, while maximum micturition pressure decreased significantly; all showing statistically significant differences ( P<0.05). Moreover, the improvements of bladder capacity, micturition volume, and maximum micturition pressure in the combination group were greater than those in the control group, among which the improvement of micturition volume in the combination group had statistically significant difference from that of the control group ( P<0.05). The USS score, the frequency of urination, and the occurrence of urgent urination and urinary incontinence in both groups decreased compared with those before treatment, all showing statistically significant differences; moreover, the combination group had better improvements in USS score, the frequency of urination, and the occurrence of urgent urination and urinary incontinence than the control group, among which the USS score, the frequency of urination, and the occurrence of urinary incontinence in the combination group had statistically significant differences from those in the control group ( P<0.05). After treatment, the ICSI and VAS scores in both groups decreased, and the two scores in the combination group were significantly lower than those in the control group, with statistically significant differences ( P<0.05). Conclusion:Hyperbaric oxygen combined with transurethral electrocoagulation has a significant effect on hemorrhagic radiation cystitis, which can effectively improve the urodynamic properties of patients, reduce USS, OABSS, ICSI, and VAS scores, and promote the prognosis.
