Dosimetric study of multi-stage radiotherapy for thoracic tumors
10.19745/j.1003-8868.2025008
- VernacularTitle:胸部肿瘤多程放疗剂量学研究
- Author:
Ting-ting LI
1
;
Yu-hai ZHANG
1
Author Information
1. 北京京西肿瘤医院,北京 100161
- Publication Type:Journal Article
- Keywords:
multi-stage radiotherapy;
thoracic tumor;
dosimetric parameter;
consistency of penetration dose;
Halcyon acce-lerator
- From:
Chinese Medical Equipment Journal
2025;46(1):44-48
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the dosimetric advantages of multi-stage radiotherapy for thoracic tumors and the staging of multi-stage radiotherapy plan.Methods Totally 18 thoracic tumor patients who underwent thoracic radiotherapy and therapy plan modification during radiotherapy from May 2022 to October 2023 at some hospital were selected,who had the plan designed with Varian Eclipse 15.6 planning system and the radiotherapy performed with volume modulated arc therapy(V M AT)technique and Halcyon accelterator.The first-stage radiotherapy plan was compared with the second-stage plan in terms of the dosime-tric parameters of the planning target volume(PTV)and organs at risk(OARs),and consistency analysis was carried out for the penetration dose of each treatment field during the first therapy stage using the 3%/2 mm criterion.Results There were no significant differences between the two plans in conformity index(CI)and homogeneity index(HI)of the target volume(all P>0.05),while the PTV of the second-stage plan was decreased significantly(P<0.05).The V5,V20 andDmeanof the both lungs and the V30 of the heart were all lowered statistically after the plans were modified(P<0.05).The penetration dose consistency decreased gradually with the increased times of treatment,and most of the patients had a mean penetration dose consistency of 80.8%at the time of interruption of the first-stage radiotherapy.Conclusions Multi-stage radiotherapy for thoracic tumors can reduce the radiation dose to OARs such as the lung,and it's the optimal timing for modifying the radiothe-rapy plan when the results of the penetration dose consistency are reduced to around 80%.[Chinese Medical Equipment Journal,2025,46(1):44-48]