Therapeutic effect of Buyang Huanwu Decoction combined with hyperbaric oxygen therapy on acute cerebral infarction of Qi deficiency and blood stasis type
10.3760/cma.j.cn311847-20200513-00199
- VernacularTitle:补阳还五汤联合高压氧治疗气虚血瘀型急性脑梗死的疗效观察
- Author:
Kewan LIU
1
;
Xiaowei LIU
1
;
Liangliang MIAO
1
;
Chengcheng CHEN
1
;
Keqiong WANG
1
;
Yuxing LIU
1
;
Houdong MEI
1
;
Yulei LIANG
1
Author Information
1. 230031 合肥，解放军联勤保障部第九○一医院
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Buyang Huanwu Decoction;
Acute cerebral infarction
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2020;27(6):691-695
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical effect of Buyang huanwu decoction combined with hyperbaric oxygen therapy on acute cerebral infarction (ACI) of qi deficiency and blood stasis type.Methods:A total of 78 patients with acute cerebral infarction of qi deficiency and blood stasis type admitted to the 901 Hospital of CPLA from June 2016 to May 2019 were selected as study objects and randomly divided into 3 groups according to random number table method: Traditional Chinese medicine (TCM) group, HBO group, and combination group ( n=26). The TCM group was treated with traditional Chinese medicine decoction on the basis of the conventional treatment of ACI; the HBO group was treated with HBO on the basis of conventional treatment of ACI; the combination group was treated with traditional Chinese medicine decoction and HBO on the basis of the conventional treatment of ACI. After 20 days of treatment, the National Institute of Health stroke scale (NIHSS) scores and TCM syndrome scores of the 3 groups were statistically analyzed according to their basic clinical characteristics. Results:There were no significantly statistical differences in terms of NIHSS score or TCM syndrome score before treatment among the 3 groups ( H=0.304, P=0.859; H=0.379, P=0.827). After treatment, the NIHSS score of the combination group was lower than those of the TCM group and the HBO group ( P’=0.033, P’=0.011). The difference of NIHSS score after treatment in the combination group was higher than those in the TCM group and the HBO group ( P’=0.025, P’=0.003). After treatment, the TCM syndrome score of the combination group was lower than those of the TCM group and the HBO group ( P’=0.016, P’=0.046). After treatment, the difference of TCM syndrome score in the combination group was higher than those in the TCM group and the HBO group ( P’=0.005, P’=0.023). The overall clinical efficacy of the combination group was better than those of the TCM group and the HBO group ( P’=0.045, P’=0.010)). Conclusion:Buyang Huanwu decoction combined with hyperbaric oxygen therapy has a synergistic effect in the treatment of ACI, which is worthy of clinical application.
