The study on the correlation between cognitive impairment of cerebral small vessel disease and white matter hyperintensity grade and cerebral atrophy grade
10.3969/j.issn.1002-1671.2025.01.001
- VernacularTitle:脑小血管病认知障碍与脑白质高信号分级及脑萎缩分级相关研究
- Author:
Ting LIU
1
;
Jin ZHI
;
Zhongzhong LIU
;
Fang WANG
;
Fengzhu MENG
;
Xuemei LIN
;
Yan WANG
Author Information
1. 西安市第一医院影像科,陕西 西安 710002
- Publication Type:Journal Article
- Keywords:
cerebral small vessel disease;
white matter hyperintensity grade;
whole cerebral cortex atrophy grade;
cognitive impairment
- From:
Journal of Practical Radiology
2025;41(1):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between cognitive impairment of cerebral small vessel disease(CSVD)and white matter hyperintensity grade and cerebral atrophy grade.Methods The data of 213 patients with CSVD were analyzed retro-spectively.The semi-quantitative Fazekas visual score of brain MR was used to evaluate the white matter hyperintensity,and cerebral atrophy was evaluated by the whole cerebral cortex atrophy grade.Mini-mental state examination(MMSE)and Montreal cognitive assessment(Mo CA)were used to evaluate each patient and to classify according to the results.Results There was a statistically sig-nificant difference in age between male and female patients with CSVD(P=0.04,t=4.288).The mean age of males[(66.5±10.3)years]was less than females[(69.5±10.0)years].There was significant difference between patients with different gender and history of hypertension(P=0.02,t=5.424).There were statistical differences between white matter hyperintensity Fazekes grade and MMSE and Mo CA scores(P<0.001,χ2=5.639;P<0.001,χ2=5.843),and there were statistical differences between whole cerebral cortex atrophy grade and MMSE score(P=0.036,χ2=2.895).Conclusion There is a certain correlation between cognitive impairment of CSVD and head MR imaging evaluation grade.
