Differential analysis of contrast agent injection volume for the diagnosis of lower extremity artery atherosclerosis in diabetes patients
10.3969/j.issn.1002-1671.2025.01.031
- VernacularTitle:对比剂注射剂量诊断糖尿病下肢动脉粥样硬化的差异性分析
- Author:
Huimin LI
1
;
Qilong CHEN
1
;
Ying YANG
1
Author Information
1. 无锡市第九人民医院放射科,江苏 无锡 214000
- Publication Type:Journal Article
- Keywords:
diabetes;
lower extremity artery atherosclerosis;
dual-energy computed tomography;
virtual monoenergetic imaging
- From:
Journal of Practical Radiology
2025;41(1):138-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the application of dual-energy CT virtual monoenergetic imaging(Mono+)technology com-bined with personalized contrast agent injection protocols in the diagnosis of lower extremity artery atherosclerosis in diabetes patients.Methods A total of 102 diabetes patients with suspected lower extremity artery atherosclerosis were selected.All patients received dual-energy CT Mono+technology combined with personalized contrast agent injection protocols.Based on personalized contrast agent injection protocols,the patients were divided into group A(34 cases,1.5 m L/kg),group B(34 cases,1.2 m L/kg),and group C(34 cases,1.0 m L/kg).All patients underwent dual-source CT scanning,and the results of ultrasound Doppler vascular imaging within one week were used as the gold standard to evaluate the consistency between dual-energy CT Mono+technology and ultra-sound Doppler vascular imaging under personalized contrast agent injection protocols.Results The CT values,signal-to-noise ratio and contrast-to-noise ratio of the abdominal iliac segment,femoral popliteal segment and lower knee segment in group B were higher than those in group A and group C(P<0.05).The CT values of the femoral popliteal and lower knee segments in group C were higher than those in group A(P<0.05).Among the 102 diabetes patients,84 were diagnosed with lower extremity artery athero-sclerosis confirmed by ultrasound Doppler vascular imaging.The positive predictive values for diagnosing lower extremity artery ath-erosclerosis in groups A,B,and C were 93.90%,97.65%,and 93.98%,respectively.The negative predictive values were 65.00%,94.14%,and 68.42%,respectively.The consistency with ultrasound Doppler vascular imaging was 0.690,0.897,and 0.715,respec-tively.Group B exhibited a higher diagnostic accuracy than groups A and C(P<0.05).Conclusion The dual-energy CT Mono+technology combined with personalized contrast agent injection protocols demonstrate good efficacy in diagnosing lower extremity artery atherosclerosis in diabetes patients,with the best imaging quality observed with the contrast agent injection protocol of 1.2 m L/kg.
