Advances in conversion therapy for hepatocellular carcinoma combined with portal vein tumor thrombus
10.3760/cma.j.cn113884-20241015-00301
- VernacularTitle:肝细胞癌合并门静脉癌栓的转化治疗进展
- Author:
Dongliang SHANG
1
;
Fei XUE
1
Author Information
1. 郑州大学人民医院（河南省人民医院）肝胆胰腺外科，郑州 450003
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Portal vein;
Conversion therapy;
Advances
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(8):628-632
- CountryChina
- Language:Chinese
-
Abstract:
Most patients with advanced hepatocellular carcinoma (HCC) had portal vein tumor thrombus (PVTT) at initial diagnosis, which is characterized by high complication rate, treatment intole-rance and poor prognosis. HCC combined with PVTT is a major challenge in the treatment of liver cancer. With progress in therapeutic concept, locoregional therapy, targeted and immunotherapy, the combination of multiple modalities for translational therapy has become a new paradigm. However, there is no widely accepted protocol for translational therapy. This article summarizes the current diagnosis and treatment of HCC combined with PVTT, and the research protocols of combined translational therapy with various modalities, aiming to provide a basis for the future clinical reference.
