Advances in the influence of the gut microbiota on metabolic disease-related vascular calcification
10.20039/j.cnki.1007-3949.2025.03.002
- VernacularTitle:肠道菌群影响代谢性疾病血管钙化的研究进展
- Author:
Qian CHEN
1
;
Ziqi TANG
1
;
Yinyuan DING
1
Author Information
1. 重庆医科大学脂质研究中心 脂糖代谢性疾病重庆市重点实验室,重庆市 400016
- Publication Type:Journal Article
- Keywords:
gut microbiota;
vascular calcification;
chronic kidney disease;
atherosclerosis;
diabetes melli-tus;
osteoporosis
- From:
Chinese Journal of Arteriosclerosis
2025;33(3):194-201
- CountryChina
- Language:Chinese
-
Abstract:
The gut microbiome actively regulates host immunity,digestive processes,and the function of the intesti-nal endocrine system.Additionally,it modulates host neural signal transmission and nutrient metabolism through metabo-lite generation.Vascular calcification involves the deposition of calcium phosphate in blood vessel walls,secondary to metabolic disorders such as chronic kidney disease,atherosclerosis,diabetes,and osteoporosis.Recent research spanning the past two decades has indicated a close correlation between shifts in the composition and functionality of the gut microbiota,along with its metabolites,and the onset of metabolic disease-related vascular calcification.This paper pres-ents a comprehensive review of the roles and mechanisms of the gut microbiota in this context.
