Diagnostic performance of MR angiography combined with CXC motif chemokine ligand 12 in ischemic stroke
10.3969/j.issn.1002-1671.2025.01.004
- VernacularTitle:MR血管成像联合CXC基序趋化因子配体12在缺血性脑卒中的诊断效能
- Author:
Ye MA
1
;
Feng LI
1
;
Shuang ZHANG
1
;
Dashuang JI
1
;
Pin XU
1
Author Information
1. 湖北文理学院附属襄阳市中心医院放射影像科,湖北 襄阳 441021
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
magnetic resonance angiography;
CXC motif chemokine ligand 12
- From:
Journal of Practical Radiology
2025;41(1):13-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy of magnetic resonance angiography(MRA)combined with CXC motif chemokine ligand 12(CXCL12)in predicting ischemic stroke in patients with transient ischemic attack(TIA).Methods A total of 225 patients with TIA were selected,and all patients underwent MRA and CXCL12 examination before treatment.The occurrence of ischemic stroke in TIA patients was counted within 1 week of treatment,the factors influencing the occurrence of ischemic stroke in TIA patients were analyzed,and the value of MRA combined with CXCL12 in predicting the occurrence of ischemic stroke in TIA patients was ana-lyzed.Results Among the 225 patients,21 of them had ischemic stroke.Multivariate logistic regression analysis showed that Essen stroke risk scale(ESRS)score,lesion site stenosis,and CXCL12 level were the factors influencing the occurrence of ischemic stroke in TIA patients(P<0.05).The receiver operating characteristic(ROC)curve showed that the sensitivity of lesion site stenosis,CXCL12 and their combination in predicting the occurrence of ischemic stroke in TIA patients was 76.19%,71.43%,and 85.71%,respectively,the specificity was 80.39%,70.10%,and 88.73%,respectively,and the area under the curve(AUC)was 0.798,0.733,and 0.895,respectively.Conclusion MRA combined with CXCL12 has good efficacy in predicting the occurrence of ischemic stroke in TIA patients.
