Research Progress of Serum Bile Acids in Gastrointestinal Diseases
10.3969/j.issn.1008-7125.2024.05.010
- VernacularTitle:血清胆汁酸在胃肠道疾病中的研究进展
- Author:
Nuo YAO
1
;
Yongquan SHI
1
Author Information
1. 空军军医大学第一附属医院消化内科(710032)
- Publication Type:Journal Article
- Keywords:
Bile Acids;
Irritable Bowel Syndrome;
Inflammatory Bowel Disease;
Digestive System Neoplasms;
Biomarkers
- From:
Chinese Journal of Gastroenterology
2024;29(5):315-320
- CountryChina
- Language:Chinese
-
Abstract:
Bile acids are synthesized in the liver and then transported to the intestine,playing important roles in the digestion and absorption of lipids.They are mainly distributed in the gallbladder,liver,gastrointestinal tract and peripheral blood.Many studies have shown that bile acids are involved in the development of various gastrointestinal diseases,including irritable bowel syndrome,inflammatory bowel disease,and gastrointestinal tumors.Serum bile acids have been widely used in the liver function monitoring,liver diseases diagnosis,and prognosis assessment.This article summarized and analyzed the physiological functions and pathophysiology of abnormal metabolism of bile acids,and the research progress of serum bile acids and gastrointestinal diseases,in order to provide a reference for further exploration of their application in clinical diagnosis and evaluation of gastrointestinal diseases.
