Clinical efficacy of microplasma radiofrequency combined with oral traditional Chinese medicine Babao Dan capsule in the treatment of hypertrophic scar
10.3760/cma.j.cn114453-20241018-00266
- VernacularTitle:微等离子射频联合口服中药八宝丹胶囊治疗增生性瘢痕的临床效果
- Author:
Ruiqi BAI
1
;
Yichen WANG
;
Guiwen ZHOU
;
Peixuan ZHANG
;
Qiang FU
;
Minliang CHEN
;
Yang YU
Author Information
1. 解放军总医院第四医学中心烧伤学部整形修复科，北京 100048
- Publication Type:Journal Article
- Keywords:
Cicatrix;
Hypertrophic scar;
Microplasma radiofrequency;
Traditional Chinese medicine;
Damp-heat constitution
- From:
Chinese Journal of Plastic Surgery
2025;41(4):366-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of microplasma radiofrequency combined with oral traditional Chinese medicine (TCM) Babao Dan capsule to improve damp-heat TCM constitution in the treatment of hypertrophic scar.Methods:A prospective randomized controlled trial method was used to recruit patients diagnosed with damp-heat TCM constitution and suffering from hypertrophic scar who admitted to the Fourth Medical Center of Chinese PLA General Hospital from March to July 2024. All patients were randomly divided into microplasma radiofrequency combined with TCM treatment group (combination group), microplasma radiofrequency (RF) treatment group (RF group), and oral TCM treatment group (TCM group). Both the combination group and the RF group were treated with a microplasma radiofrequency instrument. Transverse, longitudinal and oblique scar grinding were performed three times with 90 W power, and regular scabs appeared in the treatment area as the treatment end point. After RF treatment in the combination group and the TCM group, Babao Dan capsule was taken with regular warm water, 0.6 g each time, 3 times/day, for 3 months. The Vancouver scar scale (VSS) score (higher score indicating more severe scar), visual analogue scale (VAS) of scar pain and itch (higher score indicating more severe symptom), and TCM constitution score (higher score indicating more severe moist heat constitution) were compared before treatment and 3 months after the first treatment. SPSS 26.0 software was used for statistical analysis. Measurement data conforming to normal distribution were expressed as Mean±SD, ANOVA was used for comparison among groups, and LSD- t method was used for pair comparison between groups. Paired sample t test was used before and after treatment in the same group. Counting data were expressed as cases (%), and the χ2 test was used for inter-group comparison. P<0.05 was considered statistically significant. Results:A total of 60 patients were included, 20 in each group. There were no significant differences in gender distribution, disease course, scar area and distribution among the three groups ( P>0.05), indicating comparability. Before treatment, there were no statistically significant differences in VSS, VAS and TCM physique scores among the 3 groups ( P>0.05). After treatment, VAS scores in the 3 groups, VSS scores in combination group and RF group, TCM physique scores in combination group and TCM group were improved compared with those before treatment, and the differences were statistically significant ( P<0.05). The VSS score of the combination group was significantly lower than that of the RF group and the TCM group ( P<0.05), but there was no statistical significance between the RF group and the TCM group ( P>0.05). The pruritus VAS score of the combination group was significantly lower than that of TCM group and RF group ( P<0.05), but there was no statistical significance between RF group and TCM group ( P>0.05). There was no significant difference in pain VAS scores among the three groups after treatment ( P>0.05). The TCM physique scores of the combination group and TCM group were significantly lower than those of the RF group ( P<0.01), but there was no statistical significance between the combination group and TCM group ( P>0.05). Conclusion:Microplasma radiofrequency combined with oral Babao Dan capsule can effectively improve the VSS score, pain and pruritus of hypertrophic scars in patients with damp-heat constitution, and the effect is better than that of radiofrequency or TCM alone.
