Research Progress and Application of Organoids in Lung Cancer
- VernacularTitle:类器官在肺癌领域研究进展及应用探讨
- Author:
Yuxin ZHANG
1
;
Linxuan WANG
;
Ying ZHANG
;
Nana LI
;
Zhenhui MA
;
Mengke LI
;
Honglin LI
Author Information
- Publication Type:Journal Article
- Keywords: Organoid model; lung cancer; Traditional Chinese Medicine; Precision medicine
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(4):909-917
- CountryChina
- Language:Chinese
- Abstract: Organoids,as a three-dimensional structural model that has been rapidly developed and widely concerned in recent years,enable the key functions and microenvironment of internal organs to be simulated in the real world,and closely reflect the physiological and pathological characteristics of the natural occurrence and metastasis of tumors,providing a new platform for disease modeling,drug research and precision medicine.This paper briefly summarizes the limitations and development prospects of organoid models,analyzes the current construction and development of organoid models of lung cancer and its applicability compared with traditional models under the holistic concept of traditional Chinese medicine and the basic theory of syndrome differentiation and treatment,and discusses the application of organoid technology in the basic research of lung cancer treatment.The advantages in screening anti-tumor Chinese medicine and drug resistance research and precision medicine provide new ideas for realizing innovative breakthroughs in traditional Chinese medicine research combined with modern science and technology.
