Establishing Quantitative Traditional Chinese Medicine Diagnostic Rules of Diabetes Based on Constrained Latent Tree Analysis
- VernacularTitle:约束隐结构建立含主-次症的糖尿病胃肠湿热辨证规则
- Author:
Yulong XU
1
;
Jinhua CHEN
;
Honglei ZHU
;
Yali LYU
;
Jingqing HU
;
Lianwen ZHANG
Author Information
- Publication Type:Journal Article
- Keywords: Diagnosis rules of syndrome; Major symptoms; Secondary symptoms; Constrained Latent Tree Analysis; Quantitative
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(2):452-459
- CountryChina
- Language:Chinese
- Abstract: The classical latent structure method does not consider the influence of primary and secondary symptoms,syndromes and symptoms in the analysis and modeling of syndromes.In this paper,based on the data of damp-heat in intestine and stomach syndrome involving 1087 diabetic patients,the classical latent structure analysis was used to obtain the quantitative syndrome diagnostic rules.Then,using Constrained Latent Tree Analysis(CLTA),the quantitative syndrome diagnostic rules containing primary and secondary symptoms were obtained as follows,primary symptoms include halitosis(2.3),yellow tongue coating(2),abdominal distension(2.3),greasy tongue coating(2.1),loose stool or loose stool(1.5),red tongue(1.3),smooth pulse(1.4).Secondary symptoms include epigastric distension(1.1).Compared with the traditional latent structure analysis method,the rules established by CLTA are more compatible with the concept of differentiating primary and secondary symptoms and the common practice of TCM.The quantitative syndrome diagnostic rules of damp-heat in intestine and stomach syndrome constructed by the CLTA method have considerable objectivity in the modeling process.The diagnostic rules established were also compatible with the qualitative concept of TCM theory in stratifying primary and secondary symptoms.Finally,the diagnostic rules are obtained by logistic regression analysis,and the accuracy of the three rules is compared.The results show that the rule recognition accuracy obtained by CLTA is the highest.Therefore,the syndrome diagnostic rules of damp-heat in intestine and stomach obtained from the analysis of CLTA are in line with the constraint semantics of primary and secondary diseases and the theory of traditional Chinese medicine.
