Study on the mechanism of oxidative stress in ocular diseases and therapeutic strategies
10.13389/j.cnki.rao.2025.0044
- VernacularTitle:氧化应激在眼部疾病中的作用机制及治疗策略研究
- Author:
Canyu WANG
1
;
Ruiyu YANG
;
Yi SHAO
;
Xuan LIAO
Author Information
1. 637000 四川省南充市,川北医学院附属医院眼科,川北医学院眼视光医学院
- Publication Type:Journal Article
- Keywords:
oxidative stress;
eye disease;
pathogenesis;
reactive oxygen species;
antioxidants
- From:
Recent Advances in Ophthalmology
2025;45(3):247-252
- CountryChina
- Language:Chinese
-
Abstract:
An imbalance between oxidative and antioxidant defense mechanisms in the body triggers oxidative stress,which causes a series of damages to the body,tissues and cells.The eye is particularly susceptible to oxidative stress due to its prolonged exposure to light and its anatomical characteristics of high metabolism and oxygen consumption.In addi-tion,inflammation,aging,genetic and environmental factors can promote the production of reactive oxygen species and weaken antioxidant defense mechanisms,which are all risk factors for oxidative stress that can lead to a variety of ocular diseases.The aim of this paper is to review the mechanisms of oxidative stress in ocular diseases such as ocular surface diseases,glaucoma,cataract,and retinopathy.At the same time,the potential therapeutic approaches to these diseases by regulating oxidative stress are discussed,so as to provide new ideas and directions for the diagnosis and treatment of ocular diseases.
