Effect of Circadian Clock Genes on Circadian Rhythm of Allergic Rhinitis Based on Weiyang Theory
10.11842/wst.20240108007
- VernacularTitle:基于卫阳循行探讨生物钟基因对变应性鼻炎昼夜节律的影响
- Author:
Xi CHEN
1
;
Ran JING
1
;
Yu LI
1
;
Man YIN
1
;
Hui ZHANG
1
;
Jianfeng ZHANG
1
;
Xinrong LI
1
Author Information
1. 成都中医药大学附属医院 成都 610072
- Publication Type:Journal Article
- Keywords:
Allergic rhinitis;
Circadian rhythms;
Weiyang theory;
CLOCK gene
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2025;27(2):431-436
- CountryChina
- Language:Chinese
-
Abstract:
Allergic rhinitis(AR)affects 10%-40%of the population in the world.Because CLOCK genes regulate the circadian rhythms of AR,the symptoms in parts of the patients are aggravated in the morning and evening and relieved at moon.Although lots of studies showed that traditional Chinese medicine is effective for AR,further explores are still needed to analyze the circadian rhythm of AR based on Chinese Chronological Medicine for controlling the circadian outbreak point of symptoms of AR in daily cycle.We supposed that Weiyang might play an important role for controlling the circadian rhythm of AR with closed similarities with the tidal variation of the expressions of CLOCK genes.Thus based on Weiyang theory,we tried to clarify the mechanism of circadian rhythm of AR and explore the relationship between Weiyang and the CLOCK genes so as to further expand the treatment methods of adjusting the circadian cycle of AR with TCM and improve the corresponding therapeutic efficacy.
