Research progress of cognitive impairment associated with Moyamoya disease in adults
10.3969/j.issn.1672-5921.2025.04.005
- VernacularTitle:成人烟雾病相关认知障碍的研究进展
- Author:
Mengli XU
1
;
Lejun LI
1
Author Information
1. 215009 南京中医药大学附属苏州市中医医院脑病科
- Publication Type:Journal Article
- Keywords:
Moyamoya disease;
Cognitive impairment;
Pathogenesis;
Revascularization;
Review
- From:
Chinese Journal of Cerebrovascular Diseases
2025;22(4):256-263
- CountryChina
- Language:Chinese
-
Abstract:
Moyamoya disease(MMD)is a rare cerebral arterial steno-occlusive disease of unknown etiology.In recent years,the impact of MMD on cognitive function has gradually become an area of active investigation.The clinical manifestations of the disease predominantly involve cognitive domains such as executive function,memory and processing speed,and with the progression of the disease,some patients may develop vascular dementia.Although preliminary researches have been conducted to explore the cognitive impairment associated with MMD in adults,the underlying pathogenesis remains unclear,and the lack of standardized diagnostic and treatment protocols poses challenges in the early identification and intervention of MMD in clinical practice.This article systematically reviewed the clinical features,pathogenesis,and existing treatment options of MMD,aiming to provide a foundation for the diagnosis and treatment of patients with MMD.
