Therapeutic efficacy observation of ultrasound-guided radiofrequency ablation for liver metastasis combined with laparoscopic resection of colorectal cancer
10.3760/cma.j.cn115355-20240919-00441
- VernacularTitle:超声引导下肝转移瘤射频消融联合腹腔镜下结直肠癌切除术治疗效果观察
- Author:
Lichun WANG
1
;
Yanjun LU
1
;
Wenqi BAI
1
Author Information
1. 山西医科大学附属肿瘤医院 山西省肿瘤医院 中国医学科学院肿瘤医院山西医院结直肠外科，太原 030013
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Liver neoplasms;
Colorectal surgery;
Radiofrequency ablation;
Laparoscope
- From:
Cancer Research and Clinic
2025;37(6):407-411
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy and safety of ultrasound-guided radiofrequency ablation for liver metastasis combined with laparoscopic resection of colorectal cancer in the treatment of colorectal cancer liver metastasis (CRLM).Methods:A retrospective cohort study was conducted. Sixty-five CRLM patients who were admitted to Shanxi Province Cancer Hospital from July 2018 to July 2020 were collected and divided into two groups based on different surgical methods: the ultrasound-guided radiofrequency ablation treatment for liver metastasis combined with laparoscopic colorectal cancer resection group (study group) and the total laparoscopic surgery group (control group), with 26 and 39 cases, respectively. The postoperative hospitalization time, surgical cost, intraoperative blood loss, postoperative anal exhaust or defecation time, postoperative feeding time, incidence of postoperative complications, postoperative recurrence and survival status were compared between the two groups of patients.Results:There was no statistically significant difference in age, gender, type of colorectal cancer, number of liver metastasis, and maximum diameter of liver metastasis between the two groups of patients (all P > 0.05). The study group and the control group showed statistically significant differences in postoperative hospitalization time [(5.4±2.2) d vs. (7.0±2.5) d], surgical costs [(4.7±0.8) ten thousand yuan vs. (3.9±0.6) ten thousand yuan], intraoperative blood loss [(104±11) ml vs. (187±20) ml], postoperative anal exhaust or defecation time [(2.2±1.5) d vs. (3.5±1.3) d], and postoperative feeding time [(2.4±1.6) d vs. (3.8±1.2) d] ( t values were 2.82, 4.63, 21.95, 3.57, and 3.65, respectively, all P < 0.01). There was no statistically significant difference in the incidence of subphrenic infection, incision infection, bile leakage, postoperative wound bleeding, liver failure, postoperative 3-year recurrence rate, and postoperative 1-, 2- and 3-year survival rates between the study group and the control group (all P > 0.05). Conclusions:The effect of ultrasound-guided radiofrequency ablation for liver metastasis combined with laparoscopic resection of colorectal cancer for CRLM is comparable to that of total laparoscopic surgery, and the hospitalization time, exhaust or defecation time and feeding time are shortened, the intraoperative bleeding is less, and the surgical complications are not increased.
