Research advances in the role of exercise prescription regulating adipokine mediated obesity-related metabolic diseases
- VernacularTitle:运动处方调控脂肪因子介导肥胖相关代谢性疾病的研究进展
- Author:
Yu-xin XIAO
1
;
De-ming FU
;
Jin-mei QIN
;
Wei-zhen XUE
Author Information
- Publication Type:Journal Article
- Keywords: exercise prescription; adipokines; obesity; metabolic disorder
- From: Journal of Regional Anatomy and Operative Surgery 2025;34(5):458-462
- CountryChina
- Language:Chinese
- Abstract: Obesity is a common chronic metabolic disease mainly characterized by excessive accumulation of adipose tissue.Recently,the global prevalence of obesity-related metabolic diseases has increased significantly,seriously affecting the physical and mental health of patients.Adipokines are pleiotropic bioactive substances secreted by adipose tissue,which have physiological functions such as regulating energy metabolism,inflammatory response and insulin sensitivity.Abnormal hyperplasia of adipose tissue can induce chronic inflammatory responses in the body,stimulate the production or secretion disorders of adipokines,and alter glucose and lipid homeostasis,thereby leading to the occurrence and development of obesity-related metabolic diseases.However,the specific mechanism remains unclear.Exercise prescription is a planned exercise guidance program based on the results of the patient's physical fitness test to achieve the expected goal by adopting the prescribed exercise methods.In recent years,previous studies have found that exercise prescriptions can regulate adipokines,thereby preventing and treating obesity-related metabolic disorders,which may become a potential treatment for obesity-related metabolic diseases in clinical practice.This article reviews the mechanism and clinical effect of targeted regulation of adipokines by exercise prescriptions in the treatment of obesity-related metabolic disorders,in order to provide some new ideas and directions for finding new therapies for obesity-related metabolic diseases.
