A Case of Nivolumab-related Adrenal Cortical Insufficiency
10.3870/j.issn.1004-0781.2025.05.023
- VernacularTitle:纳武利尤单抗致相关性肾上腺皮质功能不全1例
- Author:
Beibei WANG
1
;
Xiaolin LI
;
Caiying DU
;
Jihong GENG
;
Xianghua QUAN
Author Information
1. 扬州大学附属医院药学部,扬州 225001
- Publication Type:Journal Article
- Keywords:
Nivolumab;
Immune checkpoint inhibitor;
Adrenal insufficiency;
Adverse drug reactions
- From:
Herald of Medicine
2025;44(5):814-816
- CountryChina
- Language:Chinese
-
Abstract:
This report presents a case of a 75-year-old patient with newly diagnosed gastric cancer,who had repeated symptoms of fatigue,confusion,and hyponatremia after 2 cycles of chemotherapy combined with nivolumab as neoadjuvant treat-ment and was later diagnosed with adrenal cortical insufficiency.After applying corticosteroid replacement therapy,there was im-provement,but cortisol remained low,and long-term corticosteroid therapy is needed.
