Influence Factors of Hemorrhagic Transformation after Mechanical Thrombectomy in Acute Anterior Circulation Ischemic Stroke
10.11969/j.issn.1673-548X.2025.04.026
- VernacularTitle:急性前循环缺血性脑卒中取栓术后发生出血转化的影响因素
- Author:
Zhichao YANG
1
;
Le ZHANG
;
Zhengqian HUANG
Author Information
1. 222000 徐州医科大学附属连云港医院;222500 连云港,灌南县第一人民医院
- Publication Type:Journal Article
- Keywords:
Acute ischemic stroke;
Mechanical thrombectomy;
Hemorrhagic transformation;
Influence factors
- From:
Journal of Medical Research
2025;54(4):146-150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence factors of hemorrhagic transformation in the First People's Hospital of Lianyungang in patients with acute anterior circulation ischemic stroke(AIS)after mechanical thrombectomy(MT).Methods We collected the clin-ical data of 354 AIS patients who underwent MT in the Affiliated Lianyungang Hospital of Xuzhou Medical University from January 2019 to December 2023.They were grouped according to the results of cranial CT reviewed in 24-72h after the MT,and the patients who under-went HT were the HT group,with a total of 208 patients,and the patients who did not have HT were the control group,with a total of 104 patients.The clinical differences between the two groups were compared.Measurement data were analyzed using the Mann-Whitney U test,count data were analyzed using the x2 test,and multivariate Logistic regression analysis was used to identify independent risk factors.Results Compared to control group,the patients of HT group were older,had a higher prevalence of atrial fibrillation,higher preopera-tive NIHSS scores,lower platelet counts,higher glycated hemoglobin levels,and a higher proportion of preoperative thrombolytic therapy(P＜0.05).Multivariate logistic regression analysis indicated that hemoglobin(OR=1.02,95％CI:1.01-1.03,P=0.006)and glycated hemoglobin(OR=1.24,95％CI:1.09-1.40,P＜0.001)were independent influence factors for HT.Platelet count(OR=0.99,95％CI:0.99-0.99,P=0.014)was identified as a protective factor against HT.Conclusion Preoperative hemoglo-bin,glycated hemoglobin,and platelet count are all associated with HT following MT.
