Effects of psychological state on setup errors of radiotherapy for patients with breast cancer
10.3760/cma.j.cn115355-20240710-00345
- VernacularTitle:乳腺癌患者心理状态对放疗摆位误差的影响
- Author:
Wei ZHANG
1
;
Shirui QIN
1
;
Fukui HUAN
1
;
Hongju LI
1
;
Bofei LIU
1
;
Wenbo ZHANG
1
;
Lu HOU
1
;
Kun ZHANG
1
;
Shijia WANG
1
;
Shulian WANG
1
;
Jianrong DAI
1
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院放疗科，北京 100021
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Anxiety;
Depression;
Radiotherapy;
Setup errors
- From:
Cancer Research and Clinic
2025;37(5):362-365
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of psychological state on the setup errors of radiotherapy for breast cancer patients.Methods:A prospective cohort study was conducted. A total of 193 breast cancer patients in Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from October 2022 to May 2023 were selected. Radiotherapy was performed after fixation with an integrated multi-functional device for the head, chest and abdomen. Psychological status of patients was assessed by using 9-item health questionnaire (PHQ-9) and generalized anxiety disorder 7 self-rating scale (GAD-7) before first radiotherapy, the 10th radiotherapy and the last radiotherapy. Based on the results of the questionnaires, patients were divided into psychological problem (anxiety or depression) group and non-psychological problem group. The general data and setup errors of radiotherapy in both groups were compared.Results:All the 193 patients were female, with a median age of 47 years. There were 53 patients in psychological problem group and they underwent a total of 507 image-guided procedures, with setup errors [ M ( Q1, Q3)] of 0.18 (0.07, 0.33), 0.20 (0.10, 0.33) and 0.19 (0.09, 0.30) in the left-right (X), superior-inferior (Y), and anterior-posterior (Z) directions, respectively; the remaining 140 patients in non-psychological problem group underwent 1 240 image-guided procedures, with setup errors [ M ( Q1, Q3)]of 0.17 (0.08, 0.30), 0.20 (0.10, 0.30) and 0.18 (0.09, 0.28) in the X, Y, and Z directions, respectively, and the differences were statistically significant ( Z values were -3.78, -2.00; P < 0.001, P = 0.046). Conclusions:Anxiety and depression have an influence on the setup errors of radiotherapy in patients with breast cancer. In the processs of radiotherapy for breast cancer, it is important to pay attention to the psychological status of patients.
