Analysis of Allergen Distribution in 4775 Patients in Mentougou District of Beijing
10.11969/j.issn.1673-548X.2025.04.012
- VernacularTitle:北京市门头沟区4775例患者吸入过敏原分布情况分析
- Author:
Jinfeng SHI
1
;
Lisha LI
;
Kai GUAN
Author Information
1. 102300 北京京煤集团总医院呼吸与危重症医学科
- Publication Type:Journal Article
- Keywords:
Inhaled allergen;
Intradermal test;
Distribution of allergen
- From:
Journal of Medical Research
2025;54(4):58-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the sensitization spectrum of common inhaled allergens for respiratory allergic diseases in Mento-ugou district of Beijing,and explore the safety of domestic intradermal test reagents.Methods A total of 19 kinds of inhaled allergen re-agents were used to conduct intradermal test in patients with suspected or definite respiratory allergic diseases(bronchial asthma or allergic rhinitis with bronchial asthma)who visited Department of Respiratory and Critical Care Medicine,Beijing Jingmei Group General Hospital from January 2018 to October 2021.The trends of age,gender and distribution of allergens were compared,and the safety of domestic in-tradermal test reagents were observed.Results A total of 4775 patients were conducted,the positive rate of intradermal test was 52％(2483/4775);the top 5 inhaled allergen positive rates were indoor dust with 29.78％(1422/4775),summer and autumn pollen Ⅰ with 28.06％(1340/4775),dust mite with 23.54％(1124/4775),kochia scoparia with 20.52％(980/4775),spring pollen Ⅱ with 18.03％(861/4775).The positive rate of intradermal test decreased with the increase of age.Patients with respiratory allergic diseases often combined a variety of substances allergy.Before and after CO VID-19 infection,the positive rate of allergens decreased significantly after scientific protection.Adverse effect was observed in 7 patients,the severity of the adverse reaction was all level Ⅰ.Conclusion The inhaled allergens are mainly dust,pollen and dust mite.The main allergens have not changed significantly from 2018 to 2021.Scien-tific protection can effectively reduce the incidence of allergic diseases.Domestic intradermal reagents has high safety and can serve the clinic well.
