Treatment progress of recurrent or metastatic squamous cell carcinoma of the head and neck

VernacularTitle:复发或转移性头颈部鳞状细胞癌的治疗进展
Author: Haiying ZHU ¹ ; Kun TIAN ; Lin ZHOU ; Xudong WEI
Author Information

1. 甘肃中医药大学第四附属医院耳鼻喉科，兰州　730000
Publication Type:Journal Article
Keywords: Head and neck neoplasms; Immunotherapy; Molecular targeted therapy; Concurrent chemoradiotherapy; Recurrence
From: Cancer Research and Clinic 2025;37(2):150-153
CountryChina
Language:Chinese
Abstract: With the introduction of new drugs, the treatment model for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) has changed from systemic chemotherapy to immunotherapy, targeted therapy and multidrug combination. In addition, re-irradiation and salvage surgery have shown good clinical efficacy in patients with local recurrence of light tumor load or organ metastases with local treatment conditions. This article reviews the treatment progress of R/M HNSCC, and emphasizes the individualized and precise treatment based on the patient's past treatment experience, current disease characteristics and immune and genetic status to provide rational recommendations for treatment selection of R/M HNSCC.