Research progress of in the relationship between vitamin D and early-onset type 2 diabetes mellitus combined with microangiopathy

VernacularTitle:维生素D与早发2型糖尿病合并微血管病变相关性的研究进展
Author: Wenfei ZHAO ¹ ; Airong CHEN ; Huimin REN
Author Information

1. 730000 兰州大学第二临床医学院
Publication Type:Journal Article
Keywords: Early-onset; Diabetes mellitus,type 2; Vitamin D; Diabetic retinopathy; Diabetic kindey disease; Diabetic peripheral neuropathy
From: Chinese Journal of Diabetes 2025;33(5):388-391
CountryChina
Language:Chinese
Abstract: [Summary]Early-onset DM and suboptimal glycemic control leads to irreversible damage to nerves,blood vessels,and other target organs.Vitamin D is an important calcium and phosphorus regulator in the body,and its receptor is present in various cells throughout the body,playing an integral role in many biological effects.Previous studies have identified an inverse or independent relationship between vitamin D levels and the prevalence of microangiopathic complications in patients with type 2 diabetes mellitus(T2DM).However,it remains to be investigated whether serum vitamin D levels have a contributory role in the development of microvascular complications in patients with early-onset T2DM,and whether supplementation with vitamin D has a beneficial impact on the risk of microvascular complications in early-onset T2DM.In this article,we will review the advances in the relationship between vitamin D and early-onset T2DM combined with microangiopathy.