Establishment of a nomogram model for predicting the risk of diabetes-related eye diseases in type 2 diabetes mellitus patients
10.3969/j.issn.1006-6187.2025.05.008
- VernacularTitle:2型糖尿病患者糖尿病视网膜病变及黄斑水肿发生风险列线图预测模型的研究
- Author:
Shengqing HE
1
;
Xiaobin ZHENG
1
;
Wanrui MENG
1
Author Information
1. 518116 深圳市龙岗中心医院内分泌科
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Diabetic retinopathy;
Diabetic macular edema;
Nomogram model;
Risk factors
- From:
Chinese Journal of Diabetes
2025;33(5):354-358
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors and establish a line graph model for diabetic retinopathy(DR)and diabetic macular edema(DME)in patients with type 2 diabetes mellitus(T2DM).Methods A total of 446 patients with T2DM admitted to our hospital from June 2017 to January 2020 were selected and divided into DR/DME group(n=80)and T2DM group(n=366)according to whether they were complicated with DR and DME.Univariate and multivariate analysis were performed on the clinical data to obtain the influencing factors,and a nomogram model was constructed to evaluate the model.Results The DM duration,proportion of short axial length,FPG,HbA1c,TC and LDL-C in the DR/DME group were higher than those in the T2DM group,and the age and eGFR were lower than those in the T2DM group(P<0.05).DM duration(OR 16.380,95%CI 10.697～29.133),eGFR(OR 13.510,95%CI 5.393～33.863),HbA1c(OR 2.820,95%CI 1.064～5.610)and short axial length(OR 7.062,95%CI 1.153～43.265)were the influencing factors of DR and DME in T2DM patients.The AUC of the nomogram model was 0.906.The consistency index(0.957)and calibration curve showed that the model had good discrimination and consistency.Conclusions The DM duration,eGFR,HbA1c and short eye axis are closely related to DR and DME in T2DM patients,and the column line graph model based on this analysis has high predictive efficacy.
