Advances in gene recombination of porcine reproductive and respiratory syndrome virus

VernacularTitle:猪繁殖与呼吸综合征病毒基因重组的研究进展
Author: Wenna SHUAI ¹ ; Ziqiang GUO ; Jiale LI ; Meng LUO ; Liwei LI ; Yanjun ZHOU ; Yifeng JIANG ; Wu TONG ; Guangzhi TONG ; Fei GAO
Author Information

1. 中国农业科学院上海兽医研究所,上海 200241
Publication Type:Journal Article
Keywords: PRRSV; RNA recombination; recombination type
From: Chinese Journal of Veterinary Science 2025;45(1):145-152,162
CountryChina
Language:Chinese
Abstract: Porcine reproductive and respiratory syndrome virus(PRRSV)mainly causes sow abor-tion,stillbirth,mummified fetus and respiratory symptoms in piglets.Since first reported in China in 1996,the virus complexity has increased significantly in more than 20 years of genetic evolution,bringing huge economic losses to the pig industry.In recent years,with the emergence of various PRRSV recombinant virus strains,preventing and controlling this epidemic became increasingly difficult.The purpose of this article is to comprehensively review the genome structure and func-tion of PRRSV,RNA virus recombination mechanism,main types of recombination,and the epi-demic status and recombination for the dominant epidemic PRRSV strains,in order to provide clues for in-depth research on gene recombination of PRRSV,thus providing the theoretical sup-port for formulating scientific prevention and control strategies.