Research progress on the timing of early intervention with ultra-pulsed CO 2 fractional laser for postoperative scars

VernacularTitle:超脉冲CO 2点阵激光对术后瘢痕早期干预时间选择的研究进展
Author: Yi ZOU ¹ ; Huawei OUYANG ¹
Author Information

1. 湖南省人民医院（湖南师范大学附属第一医院）整形激光美容科，长沙　410005
Publication Type:Journal Article
Keywords: Ultrapuls CO 2 fractional laser; Postoperative scars; Early intervention
From: Journal of Chinese Physician 2025;27(11):1757-1760
CountryChina
Language:Chinese
Abstract: Traditional wisdom holds that ultra-pulsed CO 2 fractional laser treatment for postoperative scars should be performed after scar maturation. However, the latest evidence suggests that early laser intervention can significantly shorten the duration of the scar immature phase, reduce angiogenesis, and inhibit scar hyperplasia. A growing number of researchers have adopted early laser intervention for postoperative scars, with intervention timings ranging from intraoperative to the inflammatory, proliferative, and remodeling phases of wound healing. These studies have demonstrated that early intervention with ultra-pulsed CO 2 fractional laser for postoperative scars-especially within the first month after surgery-can effectively improve scar appearance, reduce the risk of scar hyperplasia, and lower the incidence of adverse reactions.