Clinical efficacy of Xingqi Tongjiang tablets in treating postprandial distress syndrome of liver-stomach disharmony syndrome
10.11958/20250337
- VernacularTitle:行气通降片治疗餐后不适综合征肝胃不和证的临床疗效
- Author:
Xuemei WANG
1
;
Wei ZHANG
;
Xun ZHOU
;
Chong LIU
Author Information
1. 荆州市中医医院脾胃病科 434000
- Publication Type:Journal Article
- Keywords:
syndrome of incoordination between liver and stomach;
electrogastrography;
postprandial distress syndrome;
Xingqi Tongjiang tablets;
clinical efficacy
- From:
Tianjin Medical Journal
2025;53(5):551-555
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy of Xingqi Tongjiang tablets in treating postprandial distress syndrome(PDS)of liver-stomach disharmony syndrome and its impact on electrogastrogram indicators.Methods A total of 300 patients with PDS were prospectively selected and randomly divided into the control group(treated with mosapride citrate+placebo of Xingqi Tongjiang tablets,n=151)and the observation group(treated with mosapride citrate+Xingqi Tongjiang tablets,n=149)according to the random number table method.The levels of traditional Chinese medicine(TCM)syndrome scores,clinical efficacy,electrogastrography indicators,negative emotion scores,quality of life scores and adverse reactions were compared between the two groups.Results After treatment,the TCM syndrome scores of both groups decreased,and the scores of the observation group were lower than those of the control group(P＜0.05).The total effective rate of the observation group was higher than that of the control group(P＜0.05).After treatment,the percentages of normal gastric slow waves(NGSW)in the overall stomach and gastric antrum before and after meals of both groups increased,and the proportion of slow waves(SR)decreased.Moreover,the increased NGSW and the decreased SR in the observation group were more significant(P＜0.05).The scores of the Hamilton Anxiety Scale(HAMA)and the Hamilton Depression Scale(HAMD)decreased after treatment in both groups,and the scores of the observation group were lower(P＜0.05).The scores of the Nepean Dyspepsia Quality of Life Index(NDLQI)increased after treatment in both groups,and the scores of the observation group were higher(P＜0.05).There were no significant differences in adverse reactions between the two groups.Conclusion Xingqi Tongjiang tablets can effectively improve the electrogastrogram indicators of patients with postprandial distress syndrome of liver-stomach disharmony syndrome,and enhance clinical efficacy.
