Observation of curative effect of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease due to Yin deficiency of liver and kidney
10.11958/20250411
- VernacularTitle:杞菊地黄丸联合氟米龙滴眼液治疗肝肾阴亏型干眼症的疗效观察
- Author:
Chunli CHANG
1
;
Zeqin CHEN
1
;
Quanbao LIU
1
;
Yanfen SHENG
1
Author Information
1. 武汉市中医医院眼科 430000
- Publication Type:Journal Article
- Keywords:
xerophthalmia;
Qi Ju Di Huang pill;
fluorometholone;
ocular surface function
- From:
Tianjin Medical Journal
2025;53(5):547-551
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease(DED)due to Yin deficiency of liver and kidney and its impact on the ocular surface function of patients.Methods Ninety-two patients with DED admitted to our hospital from April 2021 to May 2024 were gathered and assigned into two groups using a random number table method,with 46 patients in each group.The conventional group was treated with fluorometholone eye drops,while the combination group was treated with Qiju Dihuang pills on the basis of the conventional group.The efficacy,tear film break up time(TBUT),length of tear infiltration,corneal fluorescein staining(FLS)and ocular surface disease index(OSDI)of DED patients were compared between the two groups,and adverse reactions were evaluated.Results After treatment,the length of TBUT and tear infiltration were significantly increased in the two groups(P＜0.05),OSDI and FLS scores were significantly decreased(P＜0.05),and changes were more significant in the combined group(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).The efficacy of the combination group was 91.30%(42/46),which was higher than that of the conventional group,76.09%(35/46)(P＜0.05).Conclusion The combination of Qiju Dihuang pill and flumilone eye drops has good therapeutic effect for patients with DED of Yin deficiency of liver and kidney.
