AHP Combined with Response Surface Method to Optimize the Simmering Process of Rhei Radix et Rhizoma and Correlation Analysis between Composition and Color
10.14148/j.issn.1672-0482.2025.0652
- VernacularTitle:层次分析结合响应面法优化煨大黄工艺及成分与色度相关性分析
- Author:
Huilian DAI
1
;
Yu DING
;
Ziyu LIANG
;
Xinyuan LIU
;
Wei HUANG
;
Chanming LIU
;
Yueqin ZHU
;
Dianhua SHI
;
Yanpeng DAI
;
Lin LI
Author Information
1. 南京中医药大学药学院,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
simmered Rhei Radix et Rhizoma;
analytic hierarchy process;
single factor-response surface method;
chroma;
corre-lation;
process
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(5):652-660
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the optimal parameters of simmered Rhei Radix et Rhizoma and the correlation between the chroma values and the intrinsic composition of simmered Rhei Radix et Rhizoma decoction pieces powder.METHODS The single-factor-response surface method was used to investigate the simmering temperature,simmering time,paper dosage and plant ash dos-age,the response surface experiment was carried out on the basis of the single factor experiment,the appearance traits,total anthraqui-nones,free anthraquinones,leachables,sennoside A and B contents were taken as indicators,the analytic hierarchy process(AHP)was used to give weights to each index,and the process was optimized.The chroma values of raw and simmered products were deter-mined by electronic eye,the correlation and regression analysis were carried out by SPSS22.0 software,and the chroma-component re-gression equation was constructed.RESULTS The optimal process of simmering Rhei Radix et Rhizoma was 140 ℃,5 times of plant ash,2 layers of wet paper wrapped and being simmered for 2.5 h.CONCLUSION The simmering process of Rhei Radix et Rhizoma optimized by AHP combined with response surface method is reasonable and feasible,the color of decoction pieces has a significant correlation with the component content,and the regression equation constructed is reliable,which can predict the intrinsic component content of decoction pieces through chroma values.
