Comparison on CT-guided percutaneous radiofrequency ablation and cryoablation combined with synchronous biopsy of pulmonary nodules
10.13929/j.issn.1672-8475.2025.05.001
- VernacularTitle:对比CT引导下经皮肺结节射频消融与冷冻消融同步活检
- Author:
Yingtian WEI
1
;
Zhenjun WANG
;
Xiao ZHANG
;
Xiaobo ZHANG
;
Xin ZHANG
;
Xiaofeng HE
;
Zhongliang ZHANG
;
Hui SUN
;
Li MA
;
Yueyong XIAO
Author Information
1. 中国人民解放军总医院第一医学中心放射诊断科,北京 100853
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
ablation techniques;
tomography,X-ray computed;
interventional therapy
- From:
Chinese Journal of Interventional Imaging and Therapy
2025;22(5):305-309
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy and safety of CT-guided percutaneous radiofrequency ablation(RFA)and cryoablation(CRYO)combined with synchronous biopsy of pulmonary nodules.Methods Totally 62 patients with pulmonary nodules who underwent CT-guided percutaneous ablation with either RFA(n=30)or argon-helium CRYO(n=32)combined with simultaneous biopsy were enrolled,and the regarding postoperative complication rates and 1-year local control outcomes were compared.Results All patients successfully completed both ablation and biopsy procedures.In RFA group,the mean diameter of lesion was(1.43±0.33)cm,and the biopsy positive rate was 90.00%(27/30).Post-biopsy intrapulmonary hemorrhage extent immediately increased by 0.60(0.28,1.63)cm.Hemoptysis,pneumothorax requiring chest tube placement and infectious cavities observed in 2(2/30,6.67%),6(6/30,20.00%)and 4 cases(4/30,13.33%),respectively,and the 1-year local control rate in RFA group was 90.00%(27/30).In CRYO group,the mean diameter of lesion was(1.59±0.34)cm,and the biopsy positive rate was 100%(32/32).Post-biopsy intrapulmonary hemorrhage extent increased by 1.20(0.60,1.83)cm.Hemoptysis occurred in 7 cases(7/32,21.88%),and pneumothorax requiring chest tube placement was noticed in 8 cases(8/32,25.00%),while no infectious cavity was observed.The 1-year local control rate in CRYO group reached 96.88%(31/32).Statistical difference of infectious cavity was found between groups(P＜0.05).Conclusion Simultaneous biopsy during CT-guided percutaneous RFA and CRYO for lung nodules were both efficient and safe,while the former with relative higher incidence of infectious cavity.
