Effect of midline approach MIS-PTLIF on lumbar function recovery and complications in patients with lumbar degenerative diseases
10.3760/cma.j.cn431274-20241021-01585
- VernacularTitle:正中入路MIS-PTLIF治疗腰椎退行性疾病患者对其腰椎功能恢复及并发症的影响
- Author:
Fengli SUN
1
;
Zhixin LIU
1
;
Ran LIU
1
;
Yingzhao QI
1
Author Information
1. 秦皇岛市第一医院骨科,秦皇岛 066000
- Publication Type:Journal Article
- Keywords:
Lumbar degenerative disease;
Lumbar interbody fusion;
Minimally invasive surgery;
Lumbar spine function
- From:
Journal of Chinese Physician
2025;27(8):1202-1207
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of midline approach minimally invasive posterior transforaminal lumbar interbody fusion (MIS-PTLIF) on lumbar function recovery and complications in patients with lumbar degenerative diseases.Methods:A total of 84 patients with lumbar degenerative diseases admitted to the First Hospital of Qinhuangdao from December 2021 to June 2023 were selected and divided into two groups according to the random number table method: 42 cases in the control group were treated with traditional open posterior lumbar interbody fusion (PLIF), and 42 cases in the observation group were treated with midline approach MIS-PTLIF. Perioperative related indicators, Visual Analogue Scale (VAS) scores, creatine phosphokinase (CPK) levels, Oswestry Disability Index (ODI) scores at different time points, and the incidence of postoperative complications were compared between the two groups.Results:The observation group was superior to the control group in operation time, incision length, intraoperative blood loss, time to get out of bed, and hospital stay (all P<0.05). There were no significant differences in preoperative VAS and ODI scores between the two groups (all P>0.05). At 1 week and 3 months after surgery, the VAS and ODI scores of both groups were significantly lower than those before surgery (all P<0.05). The VAS and ODI scores of the observation group at 1 week after surgery were significantly lower than those of the control group (all P<0.05). There was no significant difference in serum CPK level between the two groups 1 day before surgery ( P>0.05). The serum CPK levels of the observation group on the 1st, 3rd, and 5th days after surgery were significantly lower than those of the control group (all P<0.05). The serum CPK level of the observation group on the 5th day after surgery was comparable to that 1 day before surgery ( P>0.05), while that of the control group on the 5th day after surgery was still higher than that 1 day before surgery ( P<0.05). There were no significant differences in the incidence of postoperative complications and fusion rate between the two groups (all P>0.05). Conclusions:MIS-PTLIF has a good short-term effect in the treatment of lumbar degenerative diseases, which can effectively relieve postoperative pain, help the recovery of lumbar function, and its safety and fusion rate are comparable to traditional PLIF, which is worthy of clinical promotion.