Photodynamic diagnosis and therapy of peritoneal metastases in advanced ovarian cancer
10.3760/cma.j.cn431274-20241030-01638
- VernacularTitle:晚期卵巢癌腹膜转移的光动力诊断和治疗
- Author:
Mengyu LIU
1
;
Pufang CUI
;
Lin LIU
;
Jianfeng GUO
Author Information
1. 华中科技大学同济医学院附属协和医院妇产科，武汉 430022
- Publication Type:Journal Article
- Keywords:
Ovarian neoplasms;
Photodynamic therapy;
Photodynamic diagnosis;
Fluorescence-guided surgery;
Photosensitizer
- From:
Journal of Chinese Physician
2025;27(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
The clinical manifestations of ovarian cancer are occult, often diagnosed as late stage, often accompanied by peritoneal metastasis, and easy to relapse after surgery. Compared with traditional tumor treatment methods, photodynamic therapy (PDT) is a minimally invasive and tumor-targeting specific treatment method, which can not only produce photochemical reactions to destroy tumor cells and trigger immune responses, but also use its fluorescence to support photodynamic diagnosis and fluorescence-guided surgery. Clinical studies have shown that photodynamic diagnosis and photodynamic fluorescence-guided tumor cell reduction, PDT and its combination therapy have great therapeutic potential, and have been recognized and gradually applied in recent years. This article reviews the current status of PDT in the treatment of advanced ovarian cancer, and discusses its possible application prospects in order to provide a safe and effective treatment for the comprehensive treatment of clinical ovarian cancer.
