Descriptive systematic review of cervical metastasis in ovarian cancer
10.3760/cma.j.cn431274-20241213-01852
- VernacularTitle:卵巢癌宫颈转移的描述性系统评价
- Author:
Yumei GAO
1
;
Jing CAI
1
Author Information
1. 华中科技大学同济医学院附属协和医院妇产科，武汉 430022
- Publication Type:Journal Article
- Keywords:
Ovarian neoplasms;
Neoplasm metastasis;
Uterine cervical neoplasms
- From:
Journal of Chinese Physician
2025;27(1):5-10
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To systematically evaluate the clinicopathological features and diagnosis and treatment characteristics of cervical metastasis in ovarian cancer patients in order to reduce misdiagnosis and missed diagnosis.Methods:Studies on cervical metastasis of ovarian cancer were searched in PubMed, Web of Science, CNKI, SinoMed, Wanfang, and VIP databases, and the search period was from the establishment of the database to September 30, 2024. After literature screening and data extraction by two researchers, descriptive analysis was used to systematically evaluate the included studies.Results:A total of 21 studies were included, including 87 patients, of which 11 were case reports and 10 were retrospective series of case studies. Qualitative analysis showed that the most common clinical manifestations were abnormal vaginal bleeding and drainage (61.4%, 27/44). The most common pathological type was high-grade serous carcinoma (71.4%, 40/56). 97.0% (33/34) of the patients had International Federation of Gynecology and Obstetrics (FIGO) stage Ⅲ to Ⅳ. In 30.6%(19/62) of patients, the diagnosis of ovarian primary and cervical metastases was not synchronized. Among them, 17.7%(11/62) of the primary lesions were diagnosed 6(range from 1 to 26)months earlier than the metastases. 12.9%(8/62) of the primary lesions were diagnosed 1(range from 1 to 6)months later. The median overall survival was 5 months (range 1/10 to 120 months).Conclusions:Cervical metastasis of ovarian cancer is rare, its clinical manifestations can be similar to primary cervical cancer, the differential diagnosis is difficult, the overall prognosis is poor, timely and accurate diagnosis, reasonable planning and treatment of cervical metastasis of ovarian cancer are very important for the prognosis of patients.
