Clinical effect of tibial periosteal lateral distraction combined with compound Ziyin ointment in the treatment of diabetic foot
10.3760/cma.j.cn431274-20240227-00319
- VernacularTitle:胫骨骨膜侧向牵张术联合复方紫银软膏治疗糖尿病足的临床疗效
- Author:
Qiguo LIANG
1
;
Fulin DENG
;
Zunjiang ZHAO
;
Jikui GUAN
;
Dalun LYU
Author Information
1. 芜湖市第一人民医院烧伤整形科，芜湖 241000
- Publication Type:Journal Article
- Keywords:
Diabetic foot;
Tibial periosteal lateral distraction;
Compound Ziyin ointment
- From:
Journal of Chinese Physician
2025;27(1):81-85
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of tibial periosteal lateral distraction combined with compound Ziyin ointment in the treatment of diabetic foot.Methods:A total of 62 patients with diabetic foot treated in the First People′s Hospital of Wuhu from July 2022 to September 2023 were prospectively selected and divided into routine group and combination group according to random number table method, with 31 cases in each group. The conventional group was treated with tibial periosteal lateral stretch, and the combined group was treated with tibial periosteal lateral distraction combined with compound Ziyin ointment, and the treatment lasted for 2 weeks. Traditional Chinese Medicine (TCM) syndrome scores, serum inflammatory factors, growth factors, foot temperature, toe oxygen saturation, pain and quality of life scores, clinical efficacy and complications were observed before and after treatment in the two groups.Results:After treatment, TCM syndrome score, serum inflammatory factor level and pain score were lower than before treatment, serum growth factor level, life quality score, foot temperature and toe end blood oxygen saturation were higher than before treatment (all P<0.05). After treatment, the pain score, TCM main disease score, TCM secondary disease score and inflammatory factor levels in the combined group were lower than those in the conventional group (all P<0.05), and the serum growth factor level, life quality score, foot temperature and toe end blood oxygen saturation were higher than those in the conventional group (all P<0.05). The total effective rate of combined group was higher than that of conventional group [93.55%(29/31) vs 70.97%(22/31), P<0.05]. There was no significant difference in the total incidence of adverse reactions between the two groups ( P>0.05). Conclusions:Tibial periosteal lateral distraction combined with compound Ziyin ointment can improve the levels of serum inflammatory factors, growth factors, foot temperature and toe oxygen saturation, reduce TCM syndrome score and relieve pain degree, improve patients′ quality of life and clinical efficacy, and have high safety.
