Clinical Comprehensive Evaluation of MRSA Treatment Drugs in Artificial Joint Infection
10.3870/j.issn.1004-0781.2025.03.015
- VernacularTitle:人工关节耐甲氧西林金黄色葡萄球菌感染的治疗药物临床综合评价
- Author:
Xinru LIU
1
;
Menglu LI
;
Jinhong GONG
;
Yuji WANG
;
Dan SU
;
Xindie ZHOU
;
JingJing SHANG
Author Information
1. 南京医科大学附属常州第二人民医院药学部,常州 213003;大连医科大学药学院,大连 116000
- Publication Type:Journal Article
- Keywords:
Methicillin-resistant Staphylococcus aureus;
Artificial joint infection;
Clinical comprehensive evaluation;
An-alytic hierarchy process;
Delphi method
- From:
Herald of Medicine
2025;44(3):422-428
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the comprehensive value of methicillin-resistant Staphylococcus aureus(MRSA)treatment drugs in artificial joint infections from multiple perspectives and to solve the problem of MRSA infections in artificial joints.Methods Through literature research,relevant literature was retrieved and clinical studies meeting the requirements were selected and summarized.The Analytic Hierarchy Process(AHP)was applied to collect comprehensive clinical evaluation evidence and to conduct evaluations across different dimensions according to evaluation guidelines;the Delphi method combined with AHP was used for expert anonymous questionnaire evaluation,and the data was compared and analyzed.Results A clini-cal comprehensive evaluation index model for the treatment of artificial joint infections was successfully established,and the yaahp analysis software was used to score the comprehensive clinical evaluation evidence in various directions.Treatment drugs,vancomy-cin,daptomycin,and linezolid,at various levels were calculated through the software,and it was concluded that linezolid has the highest clinical comprehensive evaluation score.Conclusion Among the treatment drugs for MRSA infections in artificial joints,linezolid has a higher clinical comprehensive value and can provide a reference for the clinical treatment of MRSA infec-tions in artificial joints.
