Clinical outcomes of using half liver and whole liver inflow blood flow blockade methods in liver resection surgery:a meta-analysis
10.3969/j.issn.1009-9905.2024.12.005
- VernacularTitle:肝切除术半肝与全肝入肝血流阻断法临床结果比较的Meta分析
- Author:
Qin-yi LI
1
;
Xian-he ZHANG
1
;
Zi-qiang GE
1
;
Yu SUN-XIN
1
;
Yong-bo YU
1
;
Guo-kai TAI
1
;
Zhi-dong WANG
1
Author Information
1. 哈尔滨医科大学附属第二医院 肝胆外科(黑龙江 哈尔滨 150086)
- Publication Type:Journal Article
- Keywords:
Hepatectomy;
Hemihepatic vascular occlusion;
Total hepatic inflow occlusion;
Randomized controlled trial;
Meta-analysis
- From:
Chinese Journal of Current Advances in General Surgery
2024;27(12):948-956
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the clinical outcomes of hemihepatic inflow occlusion(HHO)and total hepatic inflow occlusion(THO)in liver resection surgery.Method:Re-trieve the Cochrane Library,PubMed,EMbase,Ovid,Web of Science,CNKI,and WanFang Data databases,and search for journal articles published from January 1,2000 to January 31,2023,on randomized controlled trials(RCTs)comparing the effects of HHO and THO in liver resection.At the same time,two researchers independently screened literature based on inclusion and exclusion cri-teria,conducted meta-analysis using RevMan 5.4 and State17PM software.Result:Fifteen RCTs were ultimately included,including 624 patients.The meta-analysis results showed that HHO re-duced serum AST(MD=-104.75,95％CI:-134.45-75.06,P＜0.05),ALT(MD=-155.37,95％CI:-182.90-127.85,P＜0.05),and TBIL(MD=-6.28,95％CI:-8.07-4.48,P＜0.05)on postoperative days 1,3,and 7 Compared to THO,the elevation of blood levels and reduction of intraoperative bleeding(MD=-66.21,95％CI:-116.49-15.94,P＜0.05)were superior.THO is superior to HHO in shortening surgical time(MD=13.94,95％CI:4.77-23.12,P＜0.05).There was no significant differ-ence between the two methods in hospital stay,hospital death rate and complication rate(P＞0.05).Conclusion:compared with THO,the application of HHO in hepatectomy has less damage to liver function and less intraoperative bleeding,but the two methods have the similar effect in terms of hospitalization time,hospital mortality rate and complication rate.
