Long term efficacy and dynamic characteristics analysis on laparoscopic fundoplication for gastroesophageal reflux cough
10.3760/cma.j.cn113855-20240603-00405
- VernacularTitle:腹腔镜胃底折叠术对胃食管反流性咳嗽的长期疗效及动力学特征分析
- Author:
Qiaosu ZHAO
1
;
Jiannan LIU
;
Meng LI
;
Zhiwei HU
;
Jimin WU
Author Information
1. 宁波市医疗中心李惠利医院（宁波大学附属李惠利医院）消化内科，宁波 315000
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux;
Cough;
Fundoplication;
Kinetics;
Laparoscopies
- From:
Chinese Journal of General Surgery
2025;40(6):463-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the safety and efficacy of laparoscopic fundoplication in the treatment of gastroesophageal reflux related cough (GERC).Methods:Clinical data of 138 GERC patients undergoing laparoscopic fundoplication at our center from Jan 2013 to Dec 2017 were analyzed and patients were followed up until Dec 2022.Results:A total of 138 patients underwent surgery successfully.The median follow-up time was 51 (7-130) months.There were no mortality,nor major complications. In 138 GERC patients, GERC was cured in 85 patients,the cure rate of fundoplication was 61.6%, and altogether 112 patients reported effective, the effective rate was 81.2%. Multivariate regression analysis showed that normal esophageal peristalsis was independent predictors of good efficacy of fundoplication[ OR=3.810(1.373,10.573), P=0.01]. Conclusions:Laparoscopic fundoplication has long term efficacy for refractory GERC. Esophageal motility is an important dynamic characteristic that affects the postoperative efficacy of GERC.
