A multicenter randomized controlled study on the effect of acellular dermal matrix combined with hydroconductive dressing on wound healing of diabetic foot

VernacularTitle:异种脱细胞基质联合自适性负压引流对糖尿病足创面愈合效果的多中心开放随机对照研究
Author: Kun ZHANG ¹ ; Guangyao YANG ; Shang JU
Author Information

1. 新乡市中心医院伤口治疗中心，新乡　453000
Publication Type:Journal Article
Keywords: Diabetic foot; Matrix; Hydroconductive dressing
From: Chinese Journal of General Surgery 2025;40(7):546-550
CountryChina
Language:Chinese
Abstract: Objective:To investigate the effect of acellular dermal matrix (ADM) combined with hydroconductive dressing (HD) on wound healing of diabetic foot.Methods:In this study, 141 admitted patients with diabetic foot from Jun 2022 to Jun 2024 were randomly divided into three groups: control group, ADM group and ADM+HD group. The clinical data of all patients were collected and the differences of each index were compared.Results:There were 47 cases in each group. After 4 weeks of treatment, there were significant differences in wound area and VAS score among the three groups ( P<0.05). The number of ADM replacement in ADM+HD group was less and the incidence of adverse reactions was lower than that in ADM group ( P<0.05). Conclusion:ADM combined with HD has significant advantages in accelerating wound healing, relieving pain, reducing the number of dressing changes and reducing the incidence of infection.