Effects of thunder-fire moxibustion combined with pulsed electromagnetic fields on motor function and bone metabolism in patients with primary osteoporosis
10.3969/j.issn.1001-1242.2025.02.010
- VernacularTitle:雷火灸联合脉冲磁场对原发性骨质疏松症患者运动功能和骨代谢的影响
- Author:
Jing LIU
1
;
Chihuan HUANG
;
Faquan JI
Author Information
1. 南京中医药大学附属医院,江苏省南京市,210029
- Publication Type:Journal Article
- Keywords:
primary osteoporosis;
pulsed electromagnetic fields;
thunder-fire moxibustion;
timed up-and-go;
bone metabolism
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(2):231-236,247
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of thunder-fire moxibustion combined with pulsed electromagnetic fields(PEMFs)on bone metabolism and motor function in individuals with primary osteoporosis.Method:Ninety patients with primary osteoporosis were randomly assigned to three groups using the envelope method:PEMFs group(n=30),thunder-fire moxibustion group(n=30),and PEMFs+thunder-fire moxibustion group(n=30).The PEMFs treatment frequency was 16Hz with an intensity of 20mT,while thunder-fire moxi-bustion was applied at bilateral Ganshu(BL18)and Shenshu(BL23).Each treatment session lasted 30 min-utes,conducted three times a week for three consecutive months.The timed up-and-go(TUG)test,serum typeⅠprocollagen amino-terminal peptide(PINP)and type Ⅰ collagen carboxy-terminal peptide(CTX-Ⅰ)were as-sessed before treatment,after 3-month treatment,and at 6-month follow-up.Bone mineral density(BMD)was measured at 6-month follow-up.Result:①Inter-group comparison:after 3-month treatment,the PEMFs+Thunder-Fire Moxibustion group showed a significant reduction in TUG time and serum CTX-Ⅰ levels compared to the PEMFs group(P<0.05),and a more significant reduction in serum PINP levels(P<0.01).At the 6-month follow-up,the TUG time in PEMFs+thunder-fire moxibustion group was significantly lower than PEMFs group(P<0.01).Compared to the thunder-fire moxibustion group,the PEMFs+thunder-fire moxibustion group serum level of CTX-Ⅰ of decreased significantly after 3-month treatment(P<0.05).②Intra-group comparison:After three months of treatment com-pared to baseline,the PEMFs group showed a significant reduction in TUG time and serum CTX-Ⅰ levels(P<0.05),while both the Thunder-Fire Moxibustion group and the PEMFs+Thunder-Fire Moxibustion group showed significant reductions in TUG time and serum PINP and CTX-Ⅰ levels(P<0.01).Comparison between 6-month follow-up and before treatment,the TUG time of PEMFs group decreased significantly(P<0.05).The TUG time and the serum level of PINP in PEMFs+thunder-fire moxibustion group significantly decreased(P<0.01).There were no significant differences observed among any of the three groups regarding total BMD measure-ments at waist and hip regions after 6-month follow-up and before treatment(P>0.05).Conclusion:The combination of Thunder-fire moxibustion and PEMFs can enhance motor function and bone metabolism indexes in patients with primary osteoporosis,BMD shows a trend of improvement.