Risk factors of central regional lymph node metastasis in micropapillary thyroid neoplasms
10.3760/cma.j.cn113855-20230731-00027
- VernacularTitle:甲状腺微小乳头状癌中央区淋巴结转移危险因素的研究
- Author:
Zhiwei LUO
1
;
Hongli JI
;
Jinshan LIAN
;
Yamei CHEN
;
Jiang GAO
;
Longlong WANG
Author Information
1. 邯郸市第一医院普外科，邯郸 056002
- Publication Type:Journal Article
- Keywords:
Thyroid cacinoma, papillary;
Lymphatic metastasis;
Risk factor
- From:
Chinese Journal of General Surgery
2025;40(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore potential risk factors for central lymph node metastasis (CLNM) in papillary thyroid microcarcinoma (PTMC).Methods:The clinicopathological data of 304 PTMC patients admitted to Baotou Cancer Hospital from Oct 2021 to Mar 2023 were retrospectively analyzed. The risk factors of CLNM were analyzed using unifactorial and multifactorial regression.Results:The rate of central regional lymph node metastasis in 304 patients with PTMC was 46.7% (142/304). Univariate analysis showed that male, age <45 years, maximum cancerous lesion diameter ≥5 mm, total cancerous lesion diameter ≥9.5 mm, anterior-posterior lesion diameter ≥5 mm, anterior-posterior lesion diameter ratio of cancerous lesions ≥0.48, breaching of thyroid capsule, number of lymph nodes on the side of cancerous lesions ≥5, and antithyroid peroxidase antibody ≤34 IU/ml were associated with CLNM (all P<0.05); Logistic multivariate regression analysis showed that. male, age <45 years, total diameter of cancer foci ≥9.5 mm ( OR=2.052, 95% CI: 1.176-3.581, P=0.011), anteroposterior diameter ratio of cancer foci ≥0.48 ( OR=2.076, 95% CI: 1.161-3.711, P=0.014), number of lymph nodes on the side of cancer foci ≥5, and anti-thyroid peroxidase antibody ≤34 IU/ml were independent risk factors for CLNM. Conclusion:Male, age ,total diameter of cancer foci, anterior-posterior diameter ratio of cancer foci, number of lymph nodes on the side of cancer foci, and anti-thyroid peroxidase antibody level are all independent risk factors for CLNM in patients with PTMC.
