The effect of left colic artery preservation on low anterior resection syndrome in patients of rectal cancer
10.3760/cma.j.cn113855-20241114-00701
- VernacularTitle:直肠癌低位前切除术中保留左结肠动脉对低位前切除综合征发生率的影响
- Author:
Junling ZHANG
1
;
Shuo FENG
;
Tao WU
;
Changyou WANG
;
Guowei CHEN
;
Yong JIANG
;
Lie SUN
;
Tao LIU
;
Jingui WANG
;
Weidong DOU
;
Yingchao WU
;
Xin WANG
Author Information
1. 北京大学第一医院胃肠外科,北京 100034
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Colonic artery;
Syndrome;
Genitourinary function;
Proctectomy
- From:
Chinese Journal of General Surgery
2025;40(2):88-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of left colonic artery (LCA) preservation on rectal cancer patients' short-term postoperative anal function and quality of life.Methods:Two-hundred ninty-two patients with rectal cancer at the Department of Gastrointestinal Surgery of Peking University First Hospital between Jan 2022 and Dec 2023 were enrolled . The patients were divided into two groups according to whether the LCA was preserved during surgery or not. The LARS scale and EORTC QLQ-CR29 quality of life questionnaire were used to assess postoperative anal function and quality of life.Results:There were no significant differences between the two groups in terms of the amount of surgical blood loss and the number of lymph node dissections in the root No. 253 group and the time to postoperative voiding (all P>0.05). However, the LARS scores at 1 and 3 months postoperatively were significantly lower in the preserved LCA group than in the LCA nonpreserved group, especially for gas incontinence, loose stool leakage, and number of bowel movements (all P<0.05). The EORTC QLQ-CR29 scores showed that the LCA preserved group recovered significantly better than the non-preserved group in terms of postoperative voiding dysfunction ( P=0.007), urinary incontinence ( P=0.006), mucus discharge ( P=0.009), and fecal incontinence symptoms ( P<0.001). Male sexual dysfunction recovery was quicker in the preserved LCA group ( P=0.043), but there was no significant difference between the two groups at 3 months postoperatively( P>0.05). Conclusion:Preservation of the left colonic artery in low anterior resection of rectal cancer helps to reduce the incidence of postoperative low anterior resection syndrome, improve genitourinary symptoms, and improve patients' quality of life.
